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MADIT trial enrolled adult patients with
2019-05-23
MADIT trial enrolled 196 adult patients with prior myocardial infarction more than 3 weeks (Q wave or elevated cardiac enzyme), with non-sustained ventricular tachycardia (a run of 3–30 of ventricular ectopic beats with a rate more than 120 beats per minute), with left ventricular ejection fraction
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DIG-11-dUTP br Discussion Zoledronic acid has been approved
2019-05-23
Discussion Zoledronic DIG-11-dUTP has been approved for prevention and treatment of osteoporosis and glucocorticoids-induced osteoporosis, treatment of Paget\'s disease, hypercalcemia, multiple myeloma and bone metastasis. In the particular case of breast cancer, it is recommended as a monthly a
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Octreotide acetate At least genes are associated with famili
2019-05-23
At least 15 genes are associated with familial LQTS, with 3 of these genes accounting for 70–75% of cases [5]. Despite advances in the understanding of the molecular basis of LQTS, challenges remain in making the clinical diagnosis. Importantly, between 10–40% of gene carriers have normal QT interva
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In an earlier study we used a questionnaire to assess
2019-05-23
In an earlier study, we used a questionnaire to assess musculoskeletal pain in patients with CML who had achieved DMR (MR4.0) and discontinued TKI treatment, including IM, nilotinib, and dasatinib [5]. Nine out of the 27 patients surveyed developed musculoskeletal pain after discontinuing TKIs. In t
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For most health care professionals
2019-05-23
For most health-care professionals, infectious-disease modelling is something of a black box. One can see the input assumptions (ie, what goes in) and the outputs (ie, what comes out), but what happens in between seems close to magic. Given their complexity, to understand any one of the models used
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br Case A year old man was referred for
2019-05-22
Case A 45-year-old man was referred for the management of sudden-onset tachycardia. He had experienced 3 episodes of palpitation attacks, lasting for a couple of hours each, during the last 6 months. A regular, wide QRS complex tachycardia (WCT) at 150beats/min with a prominent retrograde P wave
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The review Bile acid receptor link nutrient sensing
2019-05-22
The review “Bile HZ-1157 receptor link nutrient sensing to metabolic regulation” by Li and Li is focused on bile acid receptors in the regulation of hepatic glucose and lipid metabolism and inflammation. Cholestasis and NAFLD are inflammatory liver diseases. Triglycerides are non-toxic, but accumul
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will be remembered as an exceptional year in
2019-05-22
2013 will be remembered as an exceptional year in shaping our strategy to control HIV/AIDS. Indeed, a few weeks after the 30th anniversary of the discovery of the virus, a decisive step was made in deciding how to use antiretroviral therapy (ART) for treatment and prevention worldwide. New WHO publi
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Assessment of the growth of children is fundamental to paedi
2019-05-22
Assessment of the growth of children is fundamental to paediatrics. Aberrations of growth, whether too little or too much, can be signs of current or past ill health, particularly in the case of poor growth, or portend later ill health, particularly with excessive weight gain. To know whether growth
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Desde su conceptuaci n inicial en por Gustavo
2019-05-22
Desde su conceptuación inicial en 1968, por Gustavo Gutiérrez Merino —considerado “padre” y uno de los más trascendentes exponentes de esta corriente— la tl surgió como una reflexión posterior prostaglandin receptors un primer momento, consistente en la realidad misma de diversos sectores del pueblo
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Para refrendar su cr tica al uso descontextualizado y descon
2019-05-22
Para refrendar su crítica al “uso descontextualizado y descontextualizante” de la noción de los ecl, Mato impulsó el cambio de nombre del Grupo de Trabajo purchase OG-L002 “Cultura y Poder”, después de su tercera reunión en Caracas en noviembre de 2001, reunión de la cual se derivó una tercera y amp
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Data on the costs of
2019-05-22
Data on the costs of mental disorders could motivate changes in mental health services. In the UK, economists and clinical researchers showed that increasing access to evidence-based psychological services (eg, cognitive behavioural therapy) would be nearly cost-neutral for the UK Government because
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El texto tiene seis grandes secciones a
2019-05-21
El texto tiene seis grandes secciones S63845 las que se suman el “propósito y los agradecimientos” y dos índices. En la introducción, León Frías problematiza la noción de , la cual agrupa un conjunto principalmente heterogéneo de películas; para el autor esta denominación se populariza a finales de
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O quilombo caracterizado como uma associa o guerreira
2019-05-21
O quilombo é caracterizado como uma associação guerreira aberta, sem distinção de linhagens e transcultural. A transculturalidade vem das contribuições de povos distintos, com destaque para os imbangala. No ritual de iniciação dos imbangala, na inhibitor circuncisão representava o rito de passagem q
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br Authorship br Conflict of interest disclosure
2019-05-21
Authorship Conflict of interest disclosure Introduction The Aurora kinases are serine/threonine protein kinases essential for regulation of normal Blebbistatin mitosis. Aurora kinases A (AAK) and B are overexpressed in hematologic malignancies, including acute myeloid leukemia (AML) and my
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