• Countdown to concluded its tasks after the

  2019-04-22

  

  Countdown to 2015 concluded its tasks after the launch of its seventh global report at the Maternal Newborn Health conference in Mexico City, October, 2015. It is now relaunched as Countdown to 2030 (CD2030), retaining and enhancing the successful multi-institutional network with over a decade of he

• br Role of dysfunctional telomeres in activation

  2019-04-22

  

  Role of dysfunctional telomeres in activation of p38 MAPK pathway as response to genotoxic stress Telomeres are unique structures at the ends of chromosomes that are located adjacent to more gene rich sub-telomeric regions and comprised of tandem GT-rich repeats, (TTAGGG)n in humans and other ver

• Nowadays other Brazilian HIV patients were enrolled

  2019-04-22

  

  Nowadays other 20 Brazilian HIV+ patients were enrolled in the second-phase of Lu et al. clinical trial [3], and biologic samples are becoming available for novel investigation. All this considered and taken into account that the intrinsic ability of each HIV+ individual to counteract HIV-1 results

• br Practical management of perioperative anticoagulation and

  2019-04-22

  

  Practical management of perioperative anticoagulation and antiplatelet therapy in CIED surgery By integrating the current literature and the experience from our own practice, we developed a practical algorithm recently to guide the perioperative management of anticoagulation and antiplatelet ther

• br The L type calcium channel

  2019-04-22

  

  The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot

• br Conflict of interest br Introduction Bladder cancer

  2019-04-22

  

  Conflict of interest Introduction Bladder cancer is one of the most common cancers in the world. It is estimated that around 74,000 new cases of caffeic acid phenethyl ester cancer and 16,000 bladder cancer-related deaths will occur in the United States in 2015. It is prominent in men and in

• In the univariate subgroup analysis the factors that

  2019-04-22

  

  In the univariate subgroup analysis, the factors that predicted reduced survival were increased age, significant mitral regurgitation (≥ grade 2), and creatinine level (Table 4). After multivariate analysis, (+)PES followed by ICD angiotensin receptor blocker was a strong predictor of reduced morta

• El sujeto de la enunciaci n se subordina

  2019-04-22

  

  El sujeto de la enunciación se subordina glycine transporter la autoridad y dominio del príncipe y, por interpósita persona del rey, como súbdito y leal servidor: “[…] tuve por conveniente servir a vuestra alteza con este sumario brevísimo de muy difusa hystoria que de los estragos e perdiciones aca

• De esta forma siguiendo la multicitada met fora

  2019-04-22

  

  De esta forma, siguiendo la multicitada metáfora de Hemingway, el relato policiaco es solamente la punta del iceberg, mientras que los excesos de la política se encuentran debajo del mar (de lama). El relato policíaco, entonces, no es sólo un “pretexto narrativo”, o una simple guía para el lector me

• En ella se muestran los criterios

  2019-04-20

  

  En ella se muestran los criterios sobre los que se acepta negociar en los diálogos de paz en La Habana. Fuera de estas reglas de juego para la negociación, se establecen puntos en común en ella y que según Aira: “Es indiscutible que el ‘Poder’ desempeña un papel fundamental dentro de la negociación”

• br Conformational control inhibition Conformational escape r

  2019-04-20

  

  Conformational control inhibition Conformational escape resistance is a phenomenon where point mutations (such as T315I) drive the Abl kinase toward the active type I state. “Switch-control inhibitors” bind in a non-ATP-competitive fashion to residues (E282, R386) the Abl protein uses to switch b

• Interpretation Stakeholders from sectors not historically en

  2019-04-20

  

  Interpretation Stakeholders from sectors not historically engaged in health care are forming unique partnerships with common goals and a willingness to address the challenge of global cancer care. Funding None. Declaration of interests Abstract Background Since 2013 medical students from North

• br Panels A to D show intracardiac

  2019-04-19

  

  Panels A to D show intracardiac recordings of the HRA extrastimuli with A1A2 intervals of 320−290ms at a basic CL of 600ms. The AV conduction intervals were increased gradually rather than suddenly, so that an Ae with an A2–V2–Ae sequence could be provoked only at 310ms and 300ms, followed by no A

• Bone marrow DCE MRI performed at diagnosis

  2019-04-19

  

  Bone marrow DCE-MRI performed at diagnosis and complete remission of the acute myeloid leukemia (AML) patients, those multi-parametric data from DCE-MRI correlated significantly with treatment outcome. Three distinct parameters: peak enhancement ratio (Peak) to indicate tissue blood perfusion; ampli

• Our analysis also showed that there were

  2019-04-19

  

  Our analysis also showed that there were no meaningful lipid changes with anastrozle, as a surrogate for cardiovascular health. This is in keeping with the TEAM Japan [17], TEAM Greek [18] sub-studies and the SABRE trial [19], which showed that AIs have no detrimental effects on lipid parameters. Th

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